Answer: the lymphatic system.
Though poorly understood by the average healthy person, the lymphatic system is a key player in the human circulatory and immune systems. Most of us give it little thought unless something goes wrong — something like lymphedema. Lymphedema is a disease with many different causes. One of the most common ways to get lymphedema — in the U.S., at least — is as a side effect of cancer treatment. The most obvious symptom is swelling, caused by lymphatic fluid accumulating usually in an arm or leg, and sometimes also in the head, neck, abdomen and genitals. Lymphedema is progressive — it gets worse and worse with time, and there is no known cure. On the bright side, there are treatments that can make it easier to live with. The most promising of these is complete decongestive physiotherapy, or CDP.
In much of the world, the most common cause of lymphedema is infestation and damage by the parasitic disease filariasis. Filariasis is a tropical illness that produces lymphedema by infecting lymph nodes and blocking lymphatics, usually in the legs, and producing, in severe cases, elephantiasis, or grotesque swelling and skin changes of the legs and genitalia. In the United States, filariasis is not a risk. The most common causes are lymph node surgery or radiation for cancer treatment, primary (congenital) lymphedema and the swelling associated with a circulatory problem called chronic venous insufficiency, which occurs in some people with varicose veins.
When you have a sore throat and get swollen glands (lymph nodes) on the sides of your neck...the lymphatic system has been activated to fight the infection.
For all types of lymphedema, the vast majority of sufferers are women. Arm lymphedema, caused by breast cancer treatment is the most common type associated with cancer treatment, but therapy for other cancers, including uterine, cervical, prostate and malignant melanoma, can also cause lymphedema, particularly in the legs.
While it may not be as dangerous as cancer, lymphedema is progressive and irreversible. Whether because of physical disability or the embarrassment caused by swollen limbs, it can severely limit the lives of those it affects. And while it is not fatal in itself, it does put sufferers at greater risk for infections such as cellulitis, lymphangitis and septicemia that are potentially deadly. A recent study found that lymphedema increased the odds for developing erysipelas, a dangerous type of streptococcus infection, in the lower extremities 70-fold. Some people with lymphedema suffer from a condition called lymphorrhea, in which lymphatic fluid leaks through blisters in the skin. Lymphedema can be psychologically stressful for cancer patients, by serving as a constant reminder of the disease long after surgical incisions have healed and hair has grown back.
Another is the use of external pneumatic pumps to transfer lymphatic fluid. The problem here is that the minute the pump is stopped, fluid quickly flows back and reaccumulates in the limb. This is because the fluid is not directed out of the quadrant of the body where the lymphatic system is damaged. Some patients increase the pump pressure or duration of treatment, so that, in time, this treatment will damage the skin and underlying tissue.
By far the best of the new treatments is CDP, or complete decongestive physiotherapy, or CDT: complete (or complex) decongestive treatment.
By far the best of the new treatments is CDP, or complete decongestive physiotherapy, or CDT: complete (or complex) decongestive treatment. There are other variations on the name but the basic principles are the same. The treatment consists of manual lymph drainage by external massage, followed by compression bandaging to keep the swelling from reoccurring. Therapeutic exercises and meticulous skin care are also part of this program. CDP was brought to the U.S. in 1989 by Dr. Robert Lerner, formerly Chief of Surgery, Brooklyn Jewish Hospital, New York, from the Foeldi Clinic in Germany.
In CDP, a trained therapist, with a detailed understanding of the lymphatic system, massages the skin very gently in order to redirect the lymphatic flow through connecting vessels to other adjacent lymphatic systems that are normal. The next step is to bandage the limb with multilayered bandages to keep the swelling from returning. During the first, more intensive phase of the CDP treatment program, a patient would receive manual lymph drainage and bandaging once or twice a day for five days a week and remain bandaged between sessions. This would continue as long as one or two weeks for a very mild case, or for up to 12 weeks for a very severe case. As part of the intensive treatment program, patients are taught how to bandage themselves for the second or maintenance phase of the program. During maintenance, which is a lifetime commitment, patients bandage at night and wear a compression sleeve or stocking during the day.
After treatment, we also encourage normal exercise and activity for patients with certain precautions. The best type of exercise for lymphedema patients is swimming and other water exercises because the water provides tissue counter pressure on the skin lymphatics and the muscular exercise helps the lymph to flow. "Dry land" exercise like walking, running, biking or weight lifting must be done with either bandages or the compression garment in place. This is because increased muscular activity could cause increased swelling unless there is pressure on the skin to move the lymph out of the limb.
In CDP, the skin of the affected limb is treated with low pH lotion that inhibits bacterial growth. Those with lymphedema of the arm are cautioned to use gloves for gardening, dishwashing or any activity that would expose them to cuts. Manicures and removal of the nail cuticles should be strictly avoided. Those with lymphedema of the leg(s) should not walk in bare feet. For all outdoor activities, the skin should be protected with liberal applications of sunscreen. Patients are instructed to be on the lookout for the first signs of infection and should be ready to start immediately on an antibiotic, which should be kept on hand at all times.
If you have been diagnosed with lymphedema — even if the condition is hardly noticeable — it might be a good idea to begin CDP as soon as possible because CDP works best when it is started early. CDP is not for everyone. It takes a very determined, motivated patient to use this treatment to its greatest advantage. Because CDP is relatively new to the United States, your doctor may or may not be familiar with it. If necessary, you should insist on a referral to someone who is.
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