By the time most women seek treatment for epithelial ovarian cancer, the disease has already reached an advanced stage, despite the fact that they usually have no more than mild, vague symptoms. Upon diagnosis, the usual next step is surgery to remove all visible tumors, followed by chemotherapy. If the disease is particularly advanced, it may be treated with either intravenous (delivered into the blood through an IV) or intraperitoneal (placed directly inside the abdomen) chemotherapy.
One meta-analysis, however, showed that a period of infertility lasting greater than five years was associated with an increased risk of ovarian cancer.
|Drugs||Dose (mg/m2)*||Route||Interval (weeks)||Treatments (cycles)|
|Paclitaxel||135||IV||3, day 1||6|
|Carboplatin||AUC* = 5-6||IV|
|4.0||IV||3 (daily 3 3-5 days)|
|Etoposide||50||PO||3, days 14-21|