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Bottle Feeding And Ear Infections: A Formula For Disaster?
Craig Brown, M.D.
Dr. Brown is Assistant Professor of Family Practice, Southern Illinois University, and a family physician in Mt. Zion, IL. Dr. Brown reports no commercial conflict of interest.
Otitis media
(OM) is the medical name for an infection of the middle ear. While it
affects people of all ages, it is far more common in young children; in
fact, it is the number one reason that children under one year old are
taken to the doctor.
Despite advances
in drugs and other treatments, the percentage of children who develop
otitis media has remained quite steady over time. About half of all infants
will come down with an ear infection before their first birthday; and
those who do will have an increased risk of further attacks, as well as
a higher risk of developing repeated infections later in childhood.1
The disease
is more common in boys than in girls; it is also more common in whites,
in lower socioeconomic groups, in Native Americans (particularly in Alaska),
and in children born with a cleft palate and other structural problems
of the face or skull. OM is also somewhat seasonal,
more likely to occur in early spring and winter.2
How Doctors
Diagnose Otitis Media
Often the
first indication a parent has that something is wrong with their child's
ear is a higher than normal temperature and general irritability. Infants
may not eat well; older children may rub their ear. The key sign doctors
and other medical professionals look for in suspected cases of otitis
media is a loss of flexibility in the ear drum. This is detected by using
instruments that test how the ear drum responds to changes in air pressure.
The same instruments sometimes also detect bulging or redness of the ear
drum.
Causes of
Otitis Media
We do not know everything about why some children are more prone than
others to develop otitis media but researchers have identified sniffing
as at least one possible major cause.3,4,5,6,7,8,9,10 And
studies indicate that another culprit may be bottle feeding.11
When
a child uses a typical feeding bottle, lack of ventilation or inadequate
ventilation causes a vacuum to form, and this can cause problems inside
the ear. It works like this: the non-vented bottle is simply a solid walled
vessel with a nipple held in place with a cap. The cap holds the enlarged
flange end, or base of the nipple, firmly against the top of the bottle
forming a tight seal. This arrangement does not permit any air entry,
resulting in the creation of a vacuum (negative presssure) during sucking.
Fluid may only be removed by the infant in small amounts by overcoming
the stiffness of the wall of the nipple or bottle.
The vacuum
created by bottle feeding can play havoc with the ear's inner auditory
tube. Negative pressure generated in the mouth is transmitted up the tube
and into the middle ear where, as a result, fluid can build up. The increased
fluid can cause hearing difficulties and infections. Interestingly, none
of this occurs with breast feeding, which does not create any kind of
vacuum and which actually creates positive pressure within the ear.
How to Lower Your Child's Risk
for Otitis Media
Sucking on pacifiers, toys, thumbs and similar objects can cause the same
problems inside the ear as bottle feeding. The common factor in all of
these activities is that negative pressure is generated in the mouth and
the vacuum is then transferred to the middle ear. So the first step in
preventing ear infections would be to consider taking pacifiers and the
like away from children, and training them not to suck their thumbs. As
for feeding, the answer is simple -- to breast feed or, failing that,
to use special feeding bottles that are designed to prevent the creation
of negative pressure.
Not only
does negative middle ear pressure increase a child's risk for otitis media,
but severe cases of otitis media can have even worse long-term consequences.
Studies have shown a definite relationship between this kind of negative
pressure in the ear and development of more serious ear disease. It may
lead to a condition known as secretory otitis, which can cause permanent
hearing loss, along with delayed speech development. It may also contribute
to the development of other, irreversible kinds of middle ear disease
(examples include atelectasis, adhesive otitis, and cholesteatoma).
If breast
feeding is out of the question, parents should try to reduce the risk
of vacuum and air bubble formation by using feeding bottles with continuous
positive pressure at the nipple during the entire feeding cycle.
Treatment of "Non-Toxic" Otitis
Media
What happens if your child does come down with otitis media? Obviously,
he or she should be seen by a doctor. But not all cases
of otitis media need to be treated with antibiotics. In so-called "non-toxic"
cases, where the symptoms are mild and the danger of damage to the ear
remote, there is a growing consensus among doctors simply to observe infants
and make sure that the disease does not become toxic.12,
13,14
Treatment of "Toxic" Otitis Media
As with many common infections, doctors have to walk a fine line in treating
otitis media. On one hand, children with acute otitis media must be given
antibiotics; on the other hand, both because of overprescription and misuse
of antibiotics, the organisms that cause otitis media are becoming more
and more resistant to antibiotic drugs.15,16,17
For example, according to recent studies, between 30 to 60 percent of
Streptococcus pneumoniae bacteria are now partially resistant to
the antibiotics penicillin and amoxicillin. Often, antibiotics lose their
effectiveness in children who have been given them repeatedly in a short
period of time.
In
response to this problem, the U.S. Centers for Disease Control (CDC) has
given out new recommendations on how to treat otitis media more effectively
with antibiotics. To paraphrase these recommendations, if the infant has
not received antibiotics in the last month, it is recommended that the
infant be started on usual-dose or high-dose amoxicillin.
If the treatment is not working by day three, then the infant should
be given high-dose amoxicillin-clavulanate (Augmentin®)
or cefuroxime axetil (Ceftin®) or injections of ceftrianone.
For an infant
who has received antibiotics in the last month, it is recommended that
high-dose amoxicillin, high dose amoxicillin-clavulanate or cefuroxime
axetil be started. If there is no improvement by day three, treatment
options include injections of ceftrianone, clindamycin or tympanocentesis,
which means using a needle to puncture the ear drum and remove trapped
fluid. In both cases, infants are reexamined on days 10 to 28.
Conclusion
From the
point of view of keeping ears healthy and avoiding otitis media and other
infections, breast-feeding is best for infants. Just as clearly, if parents
cannot breast feed, it is critical to use feeding bottles that are designed
to prevent nipple collapse and air bubble formation. Both are indicators
that negative pressure has formed in the feeding container. Studies have
shown that this pressure can be transferred into the middle ear. Sucking
on a pacifier or a thumb can cause the same problem. Negative pressure
within the ear may lead to serious infection or other ear disease, causing
hearing impairment and a risk for delayed speech development. It may also
put a child at risk for a host of other, potentially serious ear problems.
Whether,
when and how to treat otitis media with antibiotics or other treatments
are decisions that should be made in close consultation with your doctor.
Parents can and should reduce their child's risk factors as discussed
above but children who do come down with an ear infection should see a
doctor immediately.
References
1. American
Academy of Family Physicians. (1998). Infectious diseases in children
II, in: Home Study Self-Assessment Monograph, Leawood (pp. 230). KS: American
Academy of Family Physicians. return
2. Arnold, J.E. (1996). Otitis media and its
complications. In R.E.Behrman, R. Kleigman, A.M. Arvin (Eds.) Nelson textbook
of pediatrics. (pp. 1814-1826). 15th ed. Philadelphia: W.B. Saunders.
return
3.
Falk B, & Magnuson B. (1984, May). Eustachian tube
closing failure in children with persistent middle ear effusion. Int J
Pediatr. Otorhinolaryngol, 7(2), 97-106. return
4.
Magnuson B. (1981, November). Tympanoplasty and recurrent
disease: sniff-induced high negative pressure in the middle ear space.
Am J Otolaryngol, 2(4), 277-83. return
5. Falk B, & Magnuson B. (1984, June) Evacuation
of the middle ear by sniffing: a cause of high negative pressure and development
of middle ear disease. Otolaryngol Head Neck Surg , 92(3), 312-8. return
6.
Kobayashi T, Yaginuma Y, Takahashi Y, & Takasaka
T. (1996, January). Incidence of sniff-related cholesteatomas. Acta Otolaryngol,
116(1), 74-6. return
7.
Hauser R, & Munker G. (1989, June). Sniff-induced
negative pressure--a cause for the development of middle ear diseases?
HNO, 37(6), 242-7. return
8. Falk B. (1982, May-June). Sniff-induced negative
middle ear pressure: study of a consecutive series of children with otitis
media with effusion. Am J Otolaryngol, 3(3), 155-62. return
9.
Sakakihara J, Honjo I, Fujita A, Kurata K, & Takahashi H. (1993, March)
Eustachian tube compliance in sniff-induced otitis media with effusion:
A preliminary study. Acta Otolaryngol, 113(2), 187-90. return
10.
Buckingham R.A. (1988, May-June). Patent Eustachian tube in the underaerated
middle ear: a paradox. Ann Otol Rhinol Laryngol, 97(3 pt 1), 219-21. return
11. Brown, C.E. & Magnuson B. (2000, August 11).
On the physics of the infant feeding bottle and middle ear sequela: Ear
disease in infants can be associated with bottle feeding. Int J Pediatr
Otorhinolaryngol, 54(1), 13-20. return
12.
Otitis Media Guideline Panel. (1994). Clinical practice
guideline: Otitis media with effusion in young children. Rockville, MD:
U.S. Department of Health and Human Services, Public Health Services,
Agency for Health Care Policy and Research. return
13.
Appelman, G.L., Bossen, B.C., Dunk, J.H., van de Lisdonk,
E.H., de Melker, R.A., & van Weert, H.C. (1990). Guideline: acute
otitis media. Utreche, Netherlands: Dutch College of Family Doctors, 1990.
return
14.
Damoiseaux R.A., van Balen, F.A., Hoes, A.W., Verheij,
T.J., & de Melker, R.A. (2000, February 5). Primary care based randomised,
double blind trial of amoxicillin versus placebo for acute otitis media
in children aged under 2. BMJ, 320(7231), 350-4. return
15.
Thorburn, C.E., Knott, S.J., & Edwards, D.I. (1998,
August). In vitro activities of oral beta-lactams at concentrations achieved
in humans against penicillin-susceptible and -resistant pneumococci and
potential to select resistance. Antimicrob Agents Chemother, 42(8), 1973-9.
return
16.
McCracken G.H. (1998, June). Treatment of acute otitis media in an era
of increasing microbial resistance. Pediatr Infect Dis J, 17(6), 576-9.
return
17.
Jacobs M.R., Dagan, R., Appelbaum, P.C., & Burch, D.J. (1998). Prevalence
of antimicrobial-resistant pathogens in middle ear fluid: multinational
study of 917 children with acute otitis media. Antimicrob Agents Chemother,
42(3), 589-95. return
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